Friday, February 24, 2012

Alendronate, ryzedronat and teriparatide

What is osteoporosis? Osteoporosis is a condition in which bones become weak and more prone to fracture or break. In young adulthood, men and women are fairly new bone to replace bone, broken down naturally by the body (bone). Osteoporosis develops when the body can not replace bone as fast as he broke down. In the United States is 2000000 men with osteoporosis and 12 million people at risk of disease. About one in five men over age 50 will have a bone fracture that can seriously affect the quality of life and can lead to early death. Hypogonadism (low testosterone), including those caused by treatment for prostate cancer


Chronic illness (eg hyperthyroidism [excessive thyroid hormone], renal insufficiency, hyperprolactinemia, and some cancers)


How osteoporosis is diagnosed ? Osteoporosis is BЂњsilentBЂ 'disease without overt signs and symptoms. You need to be checked for osteoporosis if you:


The most common diagnostic tool for bone mineral density (BMD) test, such as dual energy X-ray absorbtsiometrii (DRA). Blood tests can also check for abnormal levels of calcium and vitamin D, which can lead to the bones become brittle. With early detection of men with mild (osteopenia) to severe bone loss (osteoporosis) may take steps to improve their bone health and reduce the risk of fractures. How to prevent and treat osteoporosis? To limit the loss of bone mass, you need to do weight-bearing exercise and avoid drinking because too much alcohol and smoking. Your diet (as amended, if necessary) should also include enough calcium (1000 mg / day for men younger than 50 years and 1200 mg / day for those over age 50) and vitamin D (at least 400BЂ "800 IU / day). Along with lifestyle changes, you may need treatment to stop bone loss and prevent fractures. Among the few drugs approved for women only alendronate, teriparatide ryzedronat and approved of by the Food and Drug Administration United States for the treatment of osteoporosis in men. Alendronate and ryzedronat (daily or weekly pill) used to slow bone loss, while teriparatide (daily injection) stimulates the formation of new bone. However, teriparatide only approved for people who are at high risk of fractures.low immune system symptoms Alendronate, ryzedronat and teriparatide seems to be effective in men with low levels of sex hormones (hypogonadism). However, it is still unclear whether testosterone replacement therapy is useful for the treatment of osteoporosis in men. Although small studies have shown that testosterone increases bone density in men with low levels of sex hormones, there is no information that reduces the risk of fractures. What do I do with this information? Loss of bone mass is part of the aging process, but there are things you can do to help keep your bones healthy. If you are over 50 years and had a fracture or a risk factor for osteoporosis, you should have a trial defense. Because hormones play a key role in osteoporosis, you can consult an endocrinologist, a specialist in hormone related conditions. Your doctor will work with you to determine the best treatment option lasix generic side effects for you. .

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